About Us

We are a clinical-stage drug discovery company on a mission to accelerate the identification of transformative small molecule therapeutics. Backed by top-tier venture capital and fueled by a team of scientists who refuse to accept the status quo, we're building the infrastructure to discover tomorrow's medicines faster than anyone thought possible. If you thrive at the intersection of biology, engineering, and scale, we want to meet you.

The Role

We're looking for a Senior Laboratory Automation Engineer to own and advance our compound management and high-throughput screening (HTS) capabilities. This is a hands-on, high-impact role at the heart of our early drug discovery engine. You'll work side-by-side with our computational chemistry, biology, and data science teams to design, deploy, and optimize automated workflows that move compounds from library to hit with speed and precision.

What You'll Do

You'll be responsible for the end-to-end performance of our HTS platform — from scheduling liquid handling campaigns and managing our compound library, to integrating new assay formats and troubleshooting instrumentation issues before they become bottlenecks. Day to day, this means programming and maintaining liquid handlers (Hamilton, Tecan, or similar), acoustic dispensers (Echo, Labcyte), plate readers, and robotic workcells, as well as building and refining the software pipelines that tie them together.

On the compound management side, you'll oversee our DMSO compound library, ensure sample integrity, manage concentration normalization, and work with our informatics team to keep our registration and tracking systems accurate and audit-ready. You'll also play a meaningful role in assay development — partnering with biologists to miniaturize and adapt assays for primary and counter screens, and establishing robust QC metrics to ensure data quality across every run.

Beyond the bench, you'll contribute to equipment qualification, SOPs, and capacity planning as our pipeline scales. You'll be a go-to resource when something breaks, a thought partner when something could be better, and a mentor to junior engineers and technicians on the team.

What We're Looking For

• You have at least 5 years of hands-on experience in laboratory automation within a drug discovery, pharma, or biotech environment, with a strong track record in HTS and/or compound management.
• You're fluent in at least one automation scripting environment (Hamilton VENUS, Tecan EVOware, Python, or similar) and have a practical understanding of assay biology — enough to have a real conversation with a biologist about what could be going wrong at 1536-well scale.
• You bring a systems mindset: you see a workflow as something to be optimized end-to-end, not just at individual steps. You're comfortable with ambiguity and excited by the challenge of building in a fast-moving environment where the roadmap evolves.
• Experience with LIMS or compound management software is a strong plus.
• A BS or MS in biochemistry, bioengineering, chemical engineering, or a related field is expected; equivalent experience in lieu of a degree will be considered.

Why Join Us

Competitive salary and meaningful equity. Comprehensive benefits including medical, dental, vision, and generous PTO. A small, collaborative team where your work has direct and visible impact on programs. Access to state-of-the-art instrumentation and the budget to invest in what's needed to do the job right.

We are an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.